Galantamine treats the symptoms of Alzheimer's disease. May improve the ability to think and remember or slow the loss of these abilities in people who have Alzheimer's.
Galantamine is a prescription medication used to treat the symptoms of Alzheimer's disease. Galantamine belongs to a group of drugs called acetylcholinesterase inhibitors. These work by stopping a specific enzyme from breaking down acetylcholine in the brain.
This medication comes as a tablet, extended-release (long-acting) capsule, and oral (by mouth) solution. The tablets and oral solution are usually taken twice a day, with the morning and evening meals. The extended-release capsule is taken once a day in the morning with food.
Common side effects of galantamine include nausea, vomiting, and diarrhea. Galantamine can also cause dizziness. Do not drive or operate heavy machinery until you know how galantamine affects you.
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Galantamine Cautionary Labels
Uses of Galantamine
Galantamine is a prescription medication used to treat mild to moderate Alzheimer's disease, a disease that impairs memory and the ability to think and perform daily activities.
Galantamine may improve the ability to think and remember or slow the loss of these abilities in people who have Alzheimer's disease. However, galantamine will not cure Alzheimer's disease or prevent the loss of mental abilities at some time in the future.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Galantamine Brand Names
Galantamine may be found in some form under the following brand names:
Galantamine Drug Class
Galantamine is part of the drug class:
Side Effects of Galantamine
Serious side effects have been reported with galantamine. See the "Galantamine Drug Precautions" section.
Common side effects of galantamine include the following:
- Loss of appetite
- Weight loss
- Stomach upset
- Decreased heart rate
- Uncontrollable shaking in a part of your body
This is not a complete list of galantamine side effects. Ask your doctor or pharmacist for more information.
Tell your doctor if you have any side effect that bothers you or that does not go away.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- anticholinergics such as glycopyrrolate (Cuvposa, Robinul), trospium (Sanctura), oxybutynin (Anturol, Gelnique, Oxytrol, Ditropan), solifenacin (Vesicare), dicyclomine (Bentyl), propantheline (Pro-Banthine), and atropine (Atropen, Sal-Tropine)
- medications that block a protein in the body (CYP3A4) such as some macrolide antibiotics (clarithromycin, telithromycin), some HIV protease inhibitors (indinavir, nelfinavir, ritonavir, saquinavir), some HCV protease inhibitors (boceprevir, telaprevir), some azole antifungals (ketoconazole, itraconazole, posaconazole, voriconazole), conivaptan (Vaprisol), delavirdine (Rescriptor), and nefazodone
- medications that block a protein in the body (CYP2D6) such as quinidine (Qualaquin), fluoxetine (Prozac, Sarafem), amitriptyline (Elavil, Amitril), and paroxetine (Paxil)
- Cholinergics such as bethanechol (Urecholine), cevimeline (Evoxac), pilocarpine (Salagen)
This is not a complete list of drug interactions. Ask your doctor or pharmacist for more information.
Serious side effects have been reported with galantamine including the following:
- Bradycardia (slowing of the heart rate) and AV block (changes in heart rhythm. This can cause your body and your brain to not get enough oxygen. Tell your healthcare provider right away if you have some or all of the following symptoms of bradycardia and AV block:
- Fainting, or nearly fainting
- Shortness of breath
- Getting tired quickly or easily
- Chest pain
- Increase in the amount of stomach acid produced. Tell your healthcare provider right away if you have some or all of the following symptoms of having more stomach acid:
- Stomach pain or burning
- Bloody or tarry stools
- Acid reflux or heart burn
- Bladder outflow obstruction. Tell your healthcare provider right away if you have some or all of the following symptoms of bladder obstruction:
- pain in the stomach or abdomen
- pain while urinating
- Feeling that the bladder is always full
- Not being able to urinate or pee completely
- Urinating or peeing often
- Urinating slowly
- Worsening of asthma or Chronic Obstructive Pulmonary Disease (COPD). Tell your healthcare provider right away if you have some or all of the following symptoms of asthma or COPD
- Difficulty breathing
- Shortness of breath
- Difficulty catching breath
- Using inhalers more often
Galantamine can cause dizziness. Do not drive or operate heavy machinery until you know how galantamine affects you.
Do not take galantamine if you are allergic to galantamine or any of its ingredients.
Galantamine Food Interactions
Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of galantamine, there are no specific foods that you must exclude from your diet when receiving this medication.
Before taking galantamine, tell your doctor about all of your medical conditions. Especially tell your doctor if you:
- are allergic to galantamine or to any of its ingredients
- have, or have had, seizures
- have heart problems, or heart rhythm problems
- have liver problems
- have kidney problems
- will be having surgery that requires anesthesia
- only have mild cognitive impairment, and not Alzheimer's Disease
- are pregnant or breastfeeding
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
Galantamine and Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant.
The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
Galantamine falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.
Galantamine and Lactation
Tell your doctor if you are breastfeeding or plan to breastfeed.
It is not known if galantamine crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using galantamine.
Take galantamine exactly as prescribed.
This medication comes as a tablet, extended-release (long-acting) capsule, and oral (by mouth) solution. The tablets and oral solution are usually taken twice a day. The extended-release capsule is taken once a day in the morning.
Take galantamine with food.
Do not chew, divide, or break galantamine extended-release capsules. Be sure to swallow extended-release capsules whole.
If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of galantamine at the same time.
Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.
The dose your doctor recommends may be based on the following:
- the condition being treated
- other medical conditions you have
- other medications you are taking
- how you respond to this medication
- your weight
- your height
- your age
- your gender
The recommended starting dose for galantamine tablets and galantamine oral (by mouth) liquid for the treatment of Alzheimer's Disease is 4 mg twice a day. The maximum recommended dose for galantamine tablets and galantamine oral (by mouth) liquid is 12 mg twice daily.
The recommended starting dose for galantamine extended-release capsules is 8 mg once daily in the morning. The maximum recommended dose for galantamine extended-release capsules is 24 mg once daily.
If you take too much galantamine, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.
If galantamine is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.
- Store galantamine at room temperature.
- Keep this and all medicines out of the reach of children.