Reyvow

Reyvow is used to treat the symptoms of migraine headaches (severe throbbing headaches, nausea and sensitivity to sound and light). Reyvow can help eliminate migraine pain in as little as 2 hours.

Reyvow Overview

Reviewed: April 16, 2020
Updated: 

Reyvow is a prescription medication used to treat migraine symtpoms. Reyvow does not prevent migraine attacks or reduce the number of headaches you have.

Reyvow belongs to a group of medications called serotonin 5-HT1F receptor agonists (ditans). The exact way Reyvow works is not known. It is thought to work by stopping pain signals from being sent to the brain and stopping inflammation of the nerves that cause symptoms of migraine. 

This medication comes in tablet form. It is taken by mouth, with or without food, at the first sign of a migraine headache. Do not take more than one dose of Reyvow in 24 hours.

Common side effects include dizziness, sleepiness, numbness, feeling tired, and tingling. Do not drive or operate machinery until at least 8 hours after you take Reyvow, even if you feel well enough. Do not drink alcohol or take other medicines that make you drowsy while taking Reyvow.

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Reyvow Cautionary Labels

precautionsprecautions

Uses of Reyvow

Reyvow is a prescription medicine used for the acute treatment of migraine attacks with or without aura in adults.

  • Reyvow is not used as a preventive treatment of migraine.
  • It is not known if Reyvow is safe and effective in children.
  • Reyvow is a federally controlled substance (CV) because it contains lasmiditan that can be a target for people who abuse prescription medicines or street drugs. Keep Reyvow in a safe place to protect it from theft. Never give your Reyvow to anyone else, because it may harm them. Selling or giving away Reyvow is against the law. Tell your healthcare provider if you have ever abused or been dependent on alcohol, prescription medicines or street drugs.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Lasmiditan

For more information on this medication choose from the list of selections below.

Reyvow Drug Class

Reyvow is part of the drug class:

Side Effects of Reyvow

Serious side effects have been reported with Reyvow. See the "Reyvow Precautions" section.

Common side effects of Reyvow include the following:

  • Dizziness
  • Sleepiness
  • Numbness
  • Feeling tired
  • Tingling

This is not a complete list of Reyvow side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Reyvow Interactions

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Your healthcare provider will decide if you can take Reyvow with your other medicines.
Especially, tell your healthcare provider if you take: 

  • propranolol or other medicines that can lower your heart rate
  • any medicines that can increase your blood pressure
  • any medicines that make you sleepy
  • anti-depressant medicines called:
    • selective serotonin reuptake inhibitors (SSRIs)
    • serotonin norepinephrine reuptake inhibitors (SNRIs)
    • tricyclic anti-depressants (TCAs)
    • monoamine oxidase inhibitors (MAOIs)

Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure.
Know the medicines you take. Keep a list of them and show it to your healthcare provider or pharmacist when you get a new medicine.

This is not a complete list of Reyvow drug interactions. Ask your doctor or pharmacist for more information.

Reyvow Precautions

Serious side effects have been reported with Reyvow including the following:

  • serotonin syndrome. Serotonin syndrome is a rare but serious problem that can happen in people using Reyvow, especially if Reyvow is used with anti-depressant medicines called SSRIs or SNRIs. Call your healthcare provider right away if you have any of the following symptoms of serotonin syndrome:
    • mental changes such as seeing things that are not there (hallucinations), agitation, or coma
    • fast heartbeat
    • changes in blood pressure
    • high body temperature
    • tight muscles
    • trouble walking
    • nausea, vomiting, or diarrhea
  • medication overuse headache. Some people who take medicines like Reyvow for the acute treatment of migraine attacks for 10 or more days each month may have worse headaches (medication overuse headache). If your headaches get worse, your healthcare provider may decide to stop your treatment with Reyvow.

Reyvow Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Reyvow, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before you take Reyvow, tell your healthcare provider about all of your medical conditions, including if you: 

  • have liver problems
  • have high blood pressure
  • have a low heart rate
  • are allergic to lasmiditan
  • are pregnant or plan to become pregnant. It is not known if Reyvow will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Reyvow passes into your breastmilk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Reyvow and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

There are no well-done studies that have been done in humans with Reyvow. In animal studies, pregnant animals were given this medication, and the babies showed adverse effects on development related to this medication. Therefore, this medication may be used only if the potential benefits to the mother outweigh the potential risks to the unborn child.

Reyvow and Lactation

Tell your healthcare provider if you are breastfeeding or planning to breastfeed.

It is not known if Reyvow crosses into human milk. Because many medications can cross into human milk and because the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Reyvow.

Reyvow Usage

  • Take Reyvow exactly as your healthcare provider tells you to take it.
  • Your healthcare provider may change your dose. Do not change your dose without first talking to your healthcare provider.
  • Take Reyvow tablets by mouth with or without food.
  • Do not take more than one dose in a 24-hour period.
    • If you take Reyvow 50 mg, 100 mg, or 200 mg, and your headache goes away but comes back, you should not take a second dose within 24 hours.
  • Some people who take too many Reyvow tablets may have worse headaches (medication overuse headache). If your headaches get worse, your healthcare provider may decide to stop your treatment with Reyvow.
  • You should write down when you have headaches and when you take Reyvow so you can talk to your healthcare provider about how Reyvow is working for you.

Reyvow Dosage

Take this medication exactly as prescibed by your healthcare provider. Follow the directions on your prescription label carefully.

The recommended Reyvow dose is 50 mg, 100 mg, or 200 mg taken orally, as needed.

No more than one dose should be taken in 24 hours.

Reyvow Overdose

If you take too much Reyvow, call your healthcare provider or local poison control center, or seek emergency medical attention right away.

Other Requirements

  • Store Reyvow at room temperature between 68°F to 77°F (20°C to 25°C).
  • Keep Reyvow and all medicines out of the reach of children.