Viracept treats HIV infection. Do not miss any doses. Skipping doses can make it harder to treat HIV.
Viracept is a prescription medication used to treat human immunodeficiency virus (HIV) infection. Viracept is in a class of medicines called HIV protease inhibitors. Viracept works by blocking HIV protease (a protein-cutting enzyme), which is required for HIV to multiply.
This medication comes in tablet and powder forms. It is usually taken 2 to 3 times daily, with food.
Common side effects include diarrhea and nausea.
How was your experience with Viracept?
Uses of Viracept
Viracept is a prescription medicine used to treat HIV infection. HIV is the virus that causes AIDS (acquired immune deficiency syndrome).
- Viracept is always used in combination with other antiretroviral drugs in the treatment of people with HIV infection.
- Viracept is for adults and for children 2 years of age and older.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
For more information on this medication choose from the list of selections below.
Viracept Drug Class
Viracept is part of the drug class:
Side Effects of Viracept
Most of the side effects experienced with Viracept have been mild to moderate. Some serious side effects may occur. See "Drug Precautions" section.
Common side effects include:
This is not a complete list of side effects. Ask your doctor or pharmacist for more information.
Viracept may interact with other drugs, including those you take without a prescription. You must tell your healthcare provider about all medicines you are taking or planning to take including prescription and non-prescription medicines, herbal remedies and supplements and street drugs.
Do not take the following drugs because they can cause serious problems or death if taken with Viracept:
- Cordarone (amiodarone) (for irregular heartbeat)
- Orap (pimozide)
- Quinidine (for irregular heartbeat), also known as Quinaglute, Cardioquin, Quinidex, and others
- D.H.E. 45 Injection, Ergomar, Migranal, Wigraine and Cafergot (for migraine headaches) and Methergine (for bleeding after childbirth)
- Halcion (triazolam) (for sleep problem)
- Versed (midazolam) (sedative hypnotic)
- Revatio (sildenafil) (for treatment of pulmonary arterial hypertension)
- Alfuzosin (for treatment of benign prostate enlargement)
Do not take the following medicines when you take Viracept. They may reduce the levels of Viracept in the blood and make it less effective. Talk with your healthcare provider if you are currently taking these medicines because other medicines may have to be given to take their place:
- Prilosec (omeprazole) (for stomach acid reduction)
- Rifampin (also known as Rimactane, Rifadin, Rifater, or Rifamate) (for tuberculosis)
- Phenobarbital (for seizures)
- Tegretol (carbamazepine) (for seizures)
Do not take Viracept with St. John's wort (hypericum perforatum), an herbal product sold as a dietary supplement, or products containing St. John's wort. Talk with your healthcare provider if you are taking or planning to take St. John's wort. Taking St. John's wort may decrease Viracept levels and lead to increased viral load and possible resistance to Viracept.
Do not take Viracept with cholesterol-lowering medicines Mevacor (lovastatin) or Zocor (simvastatin) because of possible serious reactions.
Do not take Viracept with Serevent (salmeterol) because of possible serious reactions.
Talk to your healthcare provider before you start taking any new prescription or non-prescription medicines or herbal supplements with Viracept.
Medicines that require dose adjustments:
- It is possible that your healthcare provider may need to increase or decrease the dose of other medicines when you are also taking Viracept.
- There is also an increased risk of drug interactions between Viracept and Lipitor (atorvastatin), Crestor (rosuvastatin), Pravachol (pravastatin) and Lescol (fluvastatin); talk to your healthcare provider before you take any of these cholesterol-reducing medicines with Viracept.
- Before you take PDE5 Inhibitors, such as Viagra (sildenafil), Levitra (vardenafil) or Cialis (tadalafil) with Viracept, talk to your healthcare provider about possible drug interactions and side effects. If you take these types of drugs and Viracept together, you may be at increased risk of side effects of these drugs such as low blood pressure, visual changes, and penile erection lasting more than 4 hours. If an erection lasts longer than 4 hours, you should seek immediate medical assistance to avoid permanent damage to your penis. Your healthcare provider can explain these symptoms to you.
- Before you take Adcirca (tadalafil) with Viracept, talk to your healthcare provider since Viracept may increase the amount of tadalafil in your blood.
- Before you take Tracleer (bosentan) with Viracept, talk to your healthcare provider since Viracept may increase the amount of bosentan in your blood.
- Before you take colchicine with Viracept, talk to your healthcare provider since Viracept may increase the amount of colchicine in your blood.
- Before you take warfarin (Coumadin) with Viracept, talk to your healthcare provider since Viracept may affect the amount of warfarin in your blood.
- If you are taking both didanosine (Videx) and Viracept:
- You should take Viracept with food one hour after or more than two hours before you take Videx buffered tablets.
- If you are taking oral contraceptives ("the pill") to prevent pregnancy, you should use an additional or different type of contraception since Viracept may reduce the effectiveness of oral contraceptives.
- Non-nucleoside reverse transcriptase inhibitors (NNRTIs): Rescriptor (delavirdine) may increase the amount of Viracept in your blood and Viracept may lower the amount of Rescriptor in your blood.
- Protease Inhibitors (PIs): Viracept may increase the amount of Crixivan (indinavir), Norvir (ritonavir), and Invirase or Fortovase (saquinavir) in your blood. As a result, your healthcare provider may choose to lower the dose of Viracept or one of these other medicines or monitor certain lab tests if Viracept is taken in combination with one or more of these other medicines.
- If you are taking Mycobutin (rifabutin), your healthcare provider may lower the dose of Mycobutin.
- If you are taking Dilantin (phenytoin), your healthcare provider will need to monitor the levels of phenytoin in your blood and may need to adjust the dose of phenytoin.
Viracept Oral Powder contains aspartame, a low-calorie sweetener, and therefore should not be taken by children with phenylketonuria (PKU).
Serious side effects may occur:
- Diabetes and high blood sugar (hyperglycemia) occur in patients taking protease inhibitors such as Viracept. Some patients had diabetes before starting protease inhibitors, others did not. Some patients needed changes in their diabetes medicine. Others needed new diabetes medicine after starting their Viracept medicine.
- Changes in body fat have been seen in some patients taking antiretroviral therapy. These changes may include increased amount of fat in the upper back and neck ("buffalo hump"), breast and around the trunk. Loss of fat from the legs, arms and face may also happen. The cause and long-term health effects of these conditions are not known at this time.
- Some patients with hemophilia have increased bleeding with protease inhibitors.
- There were other side effects, some of them serious, noted in clinical studies that occurred in less than 2% of patients receiving Viracept. However, these side effects may have been due to other drugs that patients were taking or to the illness itself. Except for diarrhea, there were not many differences in side effects in patients who took Viracept along with other drugs compared with those who took only the other drugs.
Do not take Viracept if you are allergic to any ingredient in it.
Viracept Food Interactions
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Viracept there are no specific foods that you must exclude from your diet when receiving this medication.
Tell your healthcare provider if you:
- are allergic to Viracept or any other medicines, foods, preservatives, or dyes.
- are pregnant or plan to become pregnant. The effects of Viracept on pregnant women or their unborn babies are not known.
- are breastfeeding, it is very important that you speak with your healthcare provider about the best way to feed your baby. If your baby does not already have HIV, there is a chance that it can be transmitted through breast-feeding. The Centers for Disease Control and Prevention recommends that women with HIV do not breastfeed.
- have liver or kidney disease. Viracept has not been extensively studied in people with liver or kidney disease. Viracept can be used in patients with mild liver disease without any dose adjustment. Viracept should not be used in patients with either moderate or severe liver disease.
- have any other medical problems.
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
Viracept and Pregnancy
Tell your healthcare provider if you are pregnant or plan to become pregnant.
Pregnancy Category B
Viracept should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. There are no adequate and well-controlled studies in pregnant women taking Viracept.
The effects of Viracept on pregnant women or their unborn babies are not known.
Viracept and Lactation
Tell your healthcare provider if you are breastfeeding, it is very important that you speak with your healthcare provider about the best way to feed your baby. If your baby does not already have HIV, there is a chance that it can be transmitted through breast-feeding. The Centers for Disease Control and Prevention recommends that women with HIV do not breastfeed.
- You should stay under a healthcare provider's care when taking Viracept. Do not change your treatment or stop treatment without first talking with your healthcare provider.
- You must take Viracept every day exactly as your healthcare provider prescribed it. Follow the directions from your healthcare provider, exactly as written on the label.
- Adults: Each dose should always be taken with a meal to help achieve higher Viracept levels.
- Children who cannot swallow tablets may take Viracept Oral Powder or crushed tablets.
- If you or your child is unable to swallow the tablets, dissolve the tablets in a small amount of water. Once dissolved, mix the cloudy liquid well, and consume immediately. The glass should be rinsed with water and the rinse swallowed to ensure the entire dose is consumed.
- Do not change your dose or stop taking Viracept without first consulting with your healthcare provider.
- When your Viracept supply starts to run low, get in touch with your healthcare provider or pharmacy. This is very important because the amount of virus in your blood may increase if the medicine is stopped for even a short time. The virus may develop resistance to antiretroviral medications, including Viracept, but there are other antiretroviral treatment options. Talk to your healthcare provider about how to optimize your long-term treatment.
- Be sure to set up a schedule and follow it carefully.
- Only take medicine that has been prescribed specifically for you. Do not give Viracept to others or take medicine prescribed for someone else.
Preparing Viracept Oral Powder
- The oral powder may be mixed with a small amount of water, milk, formula, soy formula, soy milk, dietary supplements, or dairy foods such as pudding or ice cream. Once mixed, the entire amount must be taken to obtain the full dose. If the mixture is not consumed immediately, it must be stored under refrigeration, but storage must not exceed 6 hours. Do not heat the mixed dose once it has been prepared.
- Do not mix the powder with any acidic food or juice, such as orange or grapefruit juice, apple juice, or apple sauce, because this may create a bitter taste.
- Do not add water to bottles of oral powder.
- Viracept powder is supplied with a scoop for measuring. For help in determining the exact dose of powder for your child, please ask your doctor, nurse, pharmacist, or other healthcare provider.
If you forget to take a dose of Viracept, take it as soon as possible. However, if you skip the dose entirely, do not double the next dose. If you forget a lot of doses, talk to your healthcare provider about how you should continue taking your medicine.
The recommended adult dose of Viracept is 1250 mg (five 250 mg tablets or two 625 mg tablets) taken two times a day or 750 mg (three 250 mg tablets) taken three times a day. Each dose should always be taken with a meal to help achieve higher Viracept levels. Viracept tablets are film-coated to help make the tablets easier to swallow.
Dosing in children 2 years of age and older: The Viracept dose in children depends on their weight. The recommended oral dose of Viracept oral powder or 250 mg tablets is 45 to 55 mg/kg twice daily or 25 to 35 mg/kg three times daily. All doses should be taken with a meal. Children who cannot swallow tablets may take Viracept oral powder or crushed tablets.
If you take too much Viracept, call your local Poison Control Center or seek emergency medical attention right away.
- Keep Viracept and all other medicines out of the reach of children.
- Keep bottle closed and store at room temperature (between 59°F and 86°F) away from sources of moisture such as a sink or other damp place. Heat and moisture may reduce the effectiveness of Viracept.
- Do not keep medicine that is out of date or that you no longer need. Be sure that if you throw any medicine away, it is out of the reach of children.
- Store in original container.