- Spacol
- Spaglumic Acid
- Spantuss HD
- Sparfloxacin
- Sparine
- SparkleFresh Anticavity
- Sparteine
- Spasdel
- Spasmolin
- Spasquid
- Spastolate
- Spastrin
- Spec-T
- Spec-T Sore Throat/Cough Suppressant
- Spec-T Sore Throat/Decongestant
- Spec-tuss
- Special C
- Spectazole
- Spectinomycin
- SpectoGard
- Spectracef
- Spectrobid
- Spectrocin Plus
- Spectrum-4
- Spinosad
- Spinraza
- Spiramycin
- Spiramycin, Combinations With Other Antibacterials
- Spirapril
- Spiriva
- Spiriva Respimat
- Spironol
- Spironolactone
- Spironolactone and Hydrochlorothiazide
- Spironolactone Plus
- Sporanox
- Spravato
- Sprintec
- Spritam
- Sprix
- Sprycel