Myrbetriq is a medication used to treat overactive bladder disorder. It may take 8 weeks or longer before you feel the full benefit of this medication.

Myrbetriq Overview


Myrbetriq is a prescription medication used alone or in combination with solifenacin to treat overactive bladder.

Myrbetriq belongs to a group of drugs called beta-3 adrenergic agonists, which help the bladder muscles to relax.

This medication comes in tablet form and is taken once a day, with water. Myrbetriq can be taken with or without food.

Common side effects include increased blood pressure, cold symptoms, and headache.

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Myrbetriq Cautionary Labels


Uses of Myrbetriq

Myrbetriq is a prescription medication used to treat adults with the symptoms of overactive bladder.

This medication can be used alone or in combination with solifenacin. 

Symptoms of overactive bladder include:

  • urinary frequency (urinating often)
  • urinary urgency (a strong need to urinate right away)
  • urinary incontinence (leakage)

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.


Myrbetriq Drug Class

Myrbetriq is part of the drug class:

Side Effects of Myrbetriq

Myrbetriq may cause serious side effects. See Drug Precautions. 

The most common side effects of Myrbetriq include:

  • increased blood pressure
  • common cold symptoms (nasopharyngitis)
  • urinary tract infection
  • headache

Other side effects that may occur when Myrbetriq and solifenacin are taken together include:

  • dry mouth
  • constipation
  • fast heart rate

Tell your doctor if you have any side effect that bothers you or that does not go away or if you have hives, skin rash or itching while taking Myrbetriq.

These are not all the possible side effects of Myrbetriq. For more information, ask your doctor or pharmacist.

Myrbetriq Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Myrbetriq may affect the way other medicines work, and other medicines may affect how Myrbetriq works.

  • Medications metabolized through CYP2D6 such as metoprolol and desipramine
  • Digoxin (Lanoxin)

Tell your doctor if you take:

  • thioridazine (Mellaril or Mellaril-S)
  • flecainide (Tambocor)
  • propafenone (Rythmol)

This is not a complete list of Myrbetriq drug interactions. Ask your doctor or pharmacist for more information.

Myrbetriq Precautions

Myrbetriq may cause serious side effects including:

  • increased blood pressure. Myrbetriq may cause your blood pressure to increase or make your blood pressure worse if you have a history of high blood pressure. It is recommended your doctor check your blood pressure while you are taking Myrbetriq, particularly if you have a history of high blood pressure. 
  • inability to empty your bladder (urinary retention). Urinary retention can happen if you have bladder outlet obstruction (BOO) or if you taking other medicines to treat overactive bladder. Talk to your doctor if you are unsure if this applies to you. Tell your doctor right away if you are unable to empty your bladder.
  • angioedema. This medication may cause an allergic reaction with swelling of the lips, face, tongue, throat with or without difficulty breathing. If this occurs, stop using this medication and call your doctor right away.
  • interactions with medications metabolized through CYP2D6 such as metoprolol and desipramine. Your doctor will monitor you closely if you are taking both medications. 

Do not take Myrbetriq if you are allergic to it. 

Myrbetriq Food Interactions

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Myrbetriq, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before you take Myrbetriq, tell your doctor if you:

  • are allergic to this medication or to any of its ingredients
  • have liver problems
  • have kidney problems
  • have very high uncontrolled blood pressure
  • have trouble emptying your bladder or you have a weak urine stream
  • are pregnant or plan to become pregnant. It is not known if Myrbetriq will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if Myrbetriq passes into your breast milk. You and your doctor should decide if you will take Myrbetriq or breastfeed. You should not do both.

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. 

Myrbetriq and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

There are no studies with the use of this medication in pregnant women in order to determine the drug-associated risk for birth defects or miscarriage.

In animal studies, pregnant animals were given this medication, in large amounts, and had some babies born with problems. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Myrbetriq and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed. 

No studies have been conducted to assess the impact of Myrbetriq on milk production in humans, its presence in human breast milk, or its effects on the breastfed child. Because Myrbetriq is predicted to be excreted in human milk and because of the potential for serious adverse reactions in nursing infants, talk to your doctor about whether you should discontinue nursing or discontinue taking this medicine.

Myrbetriq Usage

Take Myrbetriq exactly as your doctor tells you to take it.

  • You should take 1 Myrbetriq tablet once a day, with water. Swallow the tablet whole. Never crush or chew it.
  • You can take Myrbetriq with or without food.
  • If you take this medication in combination with solifenacin, take them together once a day, with or without food. 
  • If you miss a dose of Myrbetriq, begin taking it again the next day. Do not take 2 doses of Myrbetriq the same day.

Myrbetriq Dosage

Take Myrbetriq exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. 

The recommended starting dose of Myrbetriq is 25 mg once daily with or without food. Myrbetriq 25 mg is effective within 8 weeks. The dose may be increased to 50 mg once daily, if needed.

Myrbetriq may be given in combination with solifenacin. In this case, you will take both together once a day. 

For those with severe kidney disease or moderate liver disease, the dose should not exceed 25 mg once daily. 

Myrbetriq Overdose

If you take too much Myrbetriq, call your local Poison Control Center or seek emergency medical attention right away.

Other Requirements

  • Store Myrbetriq at room temperature, between 59˚F to 86˚F (15˚C to 30˚C). Keep the bottle closed.
  • Safely throw away medicine that is out of date or no longer needed.
  • Keep Myrbetriq and all medicines out of the reach of children.